Anti-Macrophage Scavenger Receptor I antibody (ab217843)

Overview

  • Product name
    Anti-Macrophage Scavenger Receptor I antibody
    See all Macrophage Scavenger Receptor I primary antibodies
  • Description
    Rabbit polyclonal to Macrophage Scavenger Receptor I
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human Macrophage Scavenger Receptor I aa 230-272 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    KEEQVHLEQEIKGEVKVLNNITNDLRLKDWEHSQTLRNITLIQ


    Database link: P21757

  • Positive control
    • Human glioma and esophageal cancer tissues. Human colon carcinoma lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab217843 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize actetylated LDL.
  • Tissue specificity
    Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages.
  • Sequence similarities
    Contains 1 collagen-like domain.
    Contains 1 SRCR domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD204 antibody
    • CD204 antigen antibody
    • CD24 antibody
    • Macrophage acetylated LDL receptor I and II antibody
    • Macrophage scavenger receptor 1 antibody
    • Macrophage scavenger receptor type III antibody
    • Macrophage scavenger receptor types I and II antibody
    • Msr 1 antibody
    • MSR1 antibody
    • MSRE_HUMAN antibody
    • phSR1 antibody
    • phSR2 antibody
    • SCARA 1 antibody
    • SCARA1 antibody
    • Scavenger receptor class A member 1 antibody
    • Scavenger receptor class A, member 1 antibody
    • Scavenger receptor type A antibody
    • Scvr antibody
    • SR A antibody
    • SRA antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed paraffin-embedded Human glioma tissue, labeling Macrophage Scavenger Receptor I using ab217843 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

  • Immunohistochemical analysis of formalin-fixed paraffin-embedded Human esophageal cancer tissue, labeling Macrophage Scavenger Receptor I using ab217843 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

  • All lanes : Anti-Macrophage Scavenger Receptor I antibody (ab217843) at 1/200 dilution

    Lane 1 : Human colon carcinoma lysates
    Lane 2 : rat brain lysates

    Secondary
    goat anti-rabbit IgG antibody (H+L) HRP-conjugated at 1/3000 dilution
    Developed using the ECL technique

    Predicted band size : 41 kDa
    Observed band size : 41 kDa

    12% gel

References

ab217843 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab217843.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up