Anti-MAD2L1 binding protein antibody (ab102052)

Overview

  • Product nameAnti-MAD2L1 binding protein antibody
    See all MAD2L1 binding protein primary antibodies
  • Description
    Rabbit polyclonal to MAD2L1 binding protein
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-306 of Human MAD2L1 binding protein (NP_001003690.1).

  • Positive control
    • Mouse liver tissue lysate. Transfected 293T cell lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: None
    Constituents: 1 x PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab102052 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 31 kDa.

Target

  • FunctionMay function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
  • Sequence similaritiesBelongs to the MAD2L1BP family.
  • Developmental stageDuring the cell cycle, levels increase and then remain constant until late mitosis after which they drop.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationNucleus. Cytoplasm > cytoskeleton > spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
  • Information by UniProt
  • Database links
  • Alternative names
    • Caught by MAD2 protein antibody
    • CMT2 antibody
    • dJ261G23.1 antibody
    • KIAA0110 antibody
    • MAD2L1 binding protein antibody
    • MAD2L1 binding protein isoform 2 antibody
    • MAD2L1-binding protein antibody
    • Mad2l1bp antibody
    • MD2BP_HUMAN antibody
    • MGC11282 antibody
    • OTTHUMP00000016496 antibody
    • RP1 261G23.6 antibody
    see all

Anti-MAD2L1 binding protein antibody images

  • Anti-MAD2L1 binding protein antibody (ab102052) at 1/500 dilution + Mouse liver lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 31 kDa
  • All lanes : Anti-MAD2L1 binding protein antibody (ab102052) at 1/500 dilution

    Lane 1 : MAD2L1 transfected lysate
    Lane 2 : Non transfected lysate

    Lysates/proteins at 25 µg per lane.

    Developed using the ECL technique

    Predicted band size : 31 kDa

References for Anti-MAD2L1 binding protein antibody (ab102052)

ab102052 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"