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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 1X PBS, pH 7.2
Concentration information loading...
Protein A purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 µg/ml. Predicted molecular weight: 31 kDa.
||Use a concentration of 10 µg/ml.
May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
Belongs to the MAD2L1BP family.
During the cell cycle, levels increase and then remain constant until late mitosis after which they drop.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Nucleus. Cytoplasm > cytoskeleton > spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
Information by UniProt
- Caught by MAD2 protein antibody
- CMT2 antibody
- dJ261G23.1 antibody
Anti-MAD2L1 binding protein antibody images
References for Anti-MAD2L1 binding protein antibody (ab88611)
has not yet been referenced specifically in any publications.
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