Anti-MAD4 antibody (ab15841)

Overview

• Product name
  Anti-MAD4 antibody
  See all MAD4 primary antibodies
• Description
  Goat polyclonal to MAD4
• Specificity
  The appearance of the 22 kDa band was blocked by incubation with the immunising peptide.
• Tested applications
  Suitable for: WBmore details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide:

  GPHCRRLGRPALS

  , corresponding to C terminal amino acids 197-209 of Human MAD4.

  Run BLAST with Run BLAST with

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage buffer
  Preservative: 0.02% Sodium Azide
  Constituents: 0.5% BSA, 0.5mg/ml Tris saline. pH 7.3
• Concentration information loading...
• Purity
  Immunogen affinity purified
• Clonality
  Polyclonal
• Isotype
  IgG
• Research areas
  • Epigenetics and Nuclear Signaling
  • Transcription
  • Domain Families
  • HLH / Leucine Zipper

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Domain Families
  • HLH / Leucine Zipper
  • HLH / Leucine Zipper

Associated products

• Compatible Secondaries
  • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
  • Donkey Anti-Goat IgG H&L (HRP) (ab205723)

Applications

Target

• Function
  Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
• Sequence similarities
  Contains 1 bHLH (basic helix-loop-helix) domain.
• Cellular localization
  Nucleus.

• Target information above from: UniProt accession Q14582 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 10608 Human
  • SwissProt: Q14582 Human
  • Unigene: 655020 Human
• Alternative names
  • bHLHc12 antibody
  • Class C basic helix loop helix protein 12 antibody
  • Class C basic helix-loop-helix protein 12 antibody

  • MAD 4 antibody
  • MAD4 antibody
  • Mad4 homolog antibody
  • MAD4_HUMAN antibody
  • Max associated protein 4 antibody
  • MAX dimerization protein 4 antibody
  • Max dimerizer 4 antibody
  • Max interacting transcriptional repressor MAD4 antibody
  • Max-associated protein 4 antibody
  • Max-interacting transcriptional repressor MAD4 antibody
  • MST 149 antibody
  • MST149 antibody
  • MSTP 149 antibody
  • MSTP149 antibody
  • MXD 4 antibody
  • MXD4 antibody

  see all

Protocols

• Western blot protocols