Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Sequence
      GPHCRRLGRPALS

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45479 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-MAD4 antibody (ab15841)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • bHLHc12
    • Class C basic helix loop helix protein 12
    • Class C basic helix-loop-helix protein 12
    • MAD 4
    • MAD4
    • Mad4 homolog
    • MAD4_HUMAN
    • Max associated protein 4
    • MAX dimerization protein 4
    • Max dimerizer 4
    • Max interacting transcriptional repressor MAD4
    • Max-associated protein 4
    • Max-interacting transcriptional repressor MAD4
    • MST 149
    • MST149
    • MSTP 149
    • MSTP149
    • MXD 4
    • MXD4
    see all
  • Function
    Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
  • Sequence similarities
    Contains 1 bHLH (basic helix-loop-helix) domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab45479 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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