Anti-MAGE 1 antibody [MA454] (Biotin) (ab79475)

Overview

  • Product nameAnti-MAGE 1 antibody [MA454] (Biotin)
    See all MAGE 1 primary antibodies
  • Description
    Mouse monoclonal [MA454] to MAGE 1 (Biotin)
  • ConjugationBiotin
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat, Dog, Human
  • Immunogen

    Partially purified, full length recombinant Human MAGE 1 protein.

  • Positive control
    • Colo32 cells. Germ cells in testis.

Properties

Applications

Our Abpromise guarantee covers the use of ab79475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 34 kDa.

Target

  • FunctionMay be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
  • Tissue specificityExpressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas.
  • Sequence similaritiesContains 1 MAGE domain.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antigen MZ2 E antibody
    • Antigen MZ2-E antibody
    • Cancer/testis antigen 1.1 antibody
    • cancer/testis antigen family 1, member 1 antibody
    • CT1.1 antibody
    • MAGA1_HUMAN antibody
    • MAGE 1 antigen antibody
    • MAGE-1 antigen antibody
    • MAGE1 antibody
    • MAGE1A antibody
    • MAGEA1 antibody
    • Melanoma antigen 1 antibody
    • Melanoma antigen family A 1 (directs expression of antigen MZ2 E) antibody
    • Melanoma antigen family A 1 antibody
    • Melanoma antigen MAGE 1 antibody
    • Melanoma associated antigen 1 antibody
    • Melanoma associated antigen MZ2 E antibody
    • Melanoma-associated antigen 1 antibody
    • MGC9326 antibody
    see all

References for Anti-MAGE 1 antibody [MA454] (Biotin) (ab79475)

ab79475 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry.

I would be pleased to help answer your questions. I assume you are using the western blot application?

Regarding dilution to use the antibody in WB, the details on the online datasheet for ab79475 recom...

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Thank you for your reply.

I can confirm that this antibody has been tested successfully in WB with blocking in 5% nonfat dry milk with PBS + 0.1%Tween 20. However, please note this may require some individual optimization.

If you ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"