Overview

  • Product name
    Anti-MAGEL2 antibody
  • Description
    Rabbit polyclonal to MAGEL2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide: MQGLFYRPQG SSKERRTSSK ERRAPSKDRM IFAATFCAPK AVSAARAHLP, corresponding to C terminal amino acids 1-43 of Human MAGEL2

  • Positive control
    • A549 Cell Lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Constituents: 98% PBS, 2% Sucrose
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111954 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 59 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Relevance
    Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGE is unknown, may play a role in embryonal development and tumor transformation or aspects of tumor progression.
  • Database links
  • Alternative names
    • Mage-l2 antibody
    • MAGE-like 2 antibody
    • MAGE-like protein 2 antibody
    • MAGEL2 antibody
    • melanoma antigen-like gene 2 antibody
    • NDNL1 antibody
    • Necdin like protein 1 antibody
    • necdin-like 1 antibody
    • nM15 antibody
    • ns7 antibody
    • Protein nM15 antibody
    • PWLS antibody
    see all

Anti-MAGEL2 antibody images

  • Anti-MAGEL2 antibody (ab111954) at 1 µg/ml + A549 Cell Lysate at 10 µg

    Predicted band size : 59 kDa

References for Anti-MAGEL2 antibody (ab111954)

ab111954 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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