Overview

  • Product nameAnti-MAGI1 antibody
    See all MAGI1 primary antibodies
  • Description
    Rabbit polyclonal to MAGI1
  • SpecificityDoes not cross react with MAGI2 or MAGI3.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to amino acids 282-296 of MAGI1.

  • Positive control
    • Tested with rat brain extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab11473 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 120, 130, 170 kDa.

Target

  • RelevanceThe MAGUK (Membrane-Associated Guanylate Kinase) family of proteins is characterized by the presence of multi-PDZ and SH3 domains, and a single region of homology to Saccharomyces cerevisiae guanylate kinase (GuK) domain. All MAGUKs studied to date localize to regions of cell-cell contact such as tight junctions in epithelial cells and synaptic junctions in neurons and are believed to be involved in the assembly of multi-protein complexes via their protein-protein interaction domains. Three novel, closely related MAGUK proteins were isolated by means of different screening assays, and named MAGI1/BAP1, MAGI2/ S-SCAM /ARIP, and SLIPR/MAGI3. MAGI1 was first identified in mouse as a protein interacting with K-RasB. Three isoforms were identified, and named MAGI1a, MAGI1b, and MAGI1c, of 1139, 1171, and 1374 amino acids respectively. The isolation of a growing number of MAGI1 binding partners, together with the determination of the subcellular and tissue distribution of the different isoforms, are paving the way towards elucidation of its function.
  • Cellular localizationCell junction; cell membrane; tight junction; peripheral membrane protein. Localizes to epithelial cells tight junctions.
  • Database links
  • Alternative names
    • AIP 3 antibody
    • AIP3 antibody
    • Atrophin 1 interacting protein 3 antibody
    • BAI1 associated protein 1 antibody
    • BAIAP 1 antibody
    • BAIAP1 antibody
    • BAP 1 antibody
    • BAP1 antibody
    • Gukmi1 antibody
    • MAGI 1 antibody
    • MAGI1c antibody
    • Membrane associated guanylate kinase inverted 1 antibody
    • membrane associated guanylate kinase WW and PDZ domain containing 1 antibody
    • TNRC 19 antibody
    • TNRC19 antibody
    • Trinucleotide repeat containing gene 19 antibody
    • Trinucleotide repeat containing gene 19 protein antibody
    • WW domain containing protein 3 antibody
    • WWP 3 antibody
    • WWP3 antibody
    see all

References for Anti-MAGI1 antibody (ab11473)

ab11473 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"