• Product nameAnti-MALT1 antibody
    See all MALT1 primary antibodies
  • Description
    Rabbit polyclonal to MALT1
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide derived from an internal region of Human MALT1.

  • Positive control
    • Human tonsil and lymphoma tissues



Our Abpromise guarantee covers the use of ab93661 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration.
IHC-P 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 minutes followed by cooling at room temperature for 20 minutes.


  • FunctionEnhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.
  • Tissue specificityHighly expressed in peripheral blood mononuclear cells. Detected at lower levels in bone marrow, thymus and lymph node, and at very low levels in colon and lung.
  • Involvement in diseaseNote=A chromosomal aberration involving MALT1 is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma). Translocation t(11;18)(q21;q21) with BIRC2. This translocation is found in approximately 50% of cytogenetically abnormal low-grade MALT lymphoma.
  • Sequence similaritiesBelongs to the peptidase C14B family.
    Contains 1 death domain.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
  • Cellular localizationCytoplasm > perinuclear region. Nucleus. Shuttles between the nucleus and cytoplasm. Found in perinuclear structures together with BCL10.
  • Information by UniProt
  • Database links
  • Alternative names
    • Caspase like protein antibody
    • DKFZp434L132 antibody
    • MALT 1 antibody
    • MALT associated translocation antibody
    • MALT lymphoma associated translocation antibody
    • MALT lymphoma-associated translocation antibody
    • Malt1 antibody
    • MALT1_HUMAN antibody
    • MLT 1 antibody
    • MLT antibody
    • MLT1 antibody
    • Mucosa associated lymphoid tissue lymphoma translocation gene 1 antibody
    • Mucosa associated lymphoid tissue lymphoma translocation protein 1 antibody
    • Mucosa-associated lymphoid tissue lymphoma translocation protein 1 antibody
    • Paracaspase antibody
    see all

Anti-MALT1 antibody images

  • ab93661, at a 1/100 dilution, staining MALT1 in formalin fixed, paraffin embedded Human lymphoma tissue by Immunohistochemistry.
  • Anti-MALT1 antibody (ab93661) at 1/25 dilution + lysate prepared from HeLa cells

    Observed band size : 90 kDa (why is the actual band size different from the predicted?)

References for Anti-MALT1 antibody (ab93661)

ab93661 has not yet been referenced specifically in any publications.

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