Overview

  • Product name
    Anti-MAN1B1 antibody
  • Description
    Rabbit polyclonal to MAN1B1
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant fragment, corresponding to a sequence within amino acids 414-670 of Human MAN1B1.

  • Positive control
    • Hela (whole cell), A431 and HepG2 lysates; SCC25 (a human head and neck squamous cell carcinoma line) tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab95975 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 80 kDa.
IHC-P 1/100 - 1/250.

Target

  • Relevance
    MAN1B1 (Mannosidase, alpha, class 1B, member 1) catalyzes the first mannose-trimming step in maturation of Asn-linked oligosaccharides. It trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2), specifically converting it to Man8GlcNAc isomer B. MAN1B1 may be involved in glycoprotein quality control since it is important to target misfolded glycoproteins for degradation.
  • Cellular localization
    Endoplasmic reticulum membrane; Single-pass type II membrane protein.
  • Database links
  • Alternative names
    • Alpha 1 2 mannosidase antibody
    • Endoplasmic reticulum alpha mannosidase 1 antibody
    • Endoplasmic reticulum mannosyl oligosaccharide 1 2 alpha mannosidase 1 antibody
    • Endoplasmic reticulum mannosyl oligosaccharide 1 2 alpha mannosidase antibody
    • ER alpha 1 2 mannosidase antibody
    • Man9GlcNAc2 specific processing alpha mannosidase antibody
    • MANA ER antibody
    • Mannosidase alpha class 1B member 1 antibody
    see all

Images

  • Anti-MAN1B1 antibody (ab95975) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size : 80 kDa
  • ab95975 at 1/100 dilution staining MAN1B1 in SCC25 by Immunohistochemistry, Paraffin-embedded tissue.

References

ab95975 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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