Anti-Mannose Phosphate Isomerase antibody (ab67357)

Overview

  • Product nameAnti-Mannose Phosphate Isomerase antibody
    See all Mannose Phosphate Isomerase primary antibodies
  • Description
    Mouse polyclonal to Mannose Phosphate Isomerase
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-423 of Human Mannose Phosphate Isomerase

  • Positive control
    • Mannose Phosphate Isomerase transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab67357 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/500 - 1/1000. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa).
    Detection Pair.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInvolved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
    • Tissue specificityExpressed in all tissues, but more abundant in heart, brain and skeletal muscle.
    • PathwayNucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2.
    • Involvement in diseaseDefects in MPI are the cause of congenital disorder of glycosylation type 1B (CDG1B) [MIM:602579]; also known as carbohydrate-deficient glycoprotein syndrome type Ib (CDGS1B). Congenital disorders of glycosylation are metabolic deficiencies in glycoprotein biosynthesis that usually cause severe mental and psychomotor retardation. They are characterized by under-glycosylated serum glycoproteins. CDG1B is clinically characterized by protein-losing enteropathy.
    • Sequence similaritiesBelongs to the mannose-6-phosphate isomerase type 1 family.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • PMI1 antibody
      • CDG1B antibody
      • FLJ39201 antibody
      • Mannose 6 phosphate isomerase antibody
      • Mannose-6-phosphate isomerase antibody
      • MANNOSEPHOSPHATE ISOMERASE antibody
      • MGC94106 antibody
      • MPI antibody
      • MPI_HUMAN antibody
      • Phosphohexomutase antibody
      • phosphomannose isomerase 1 antibody
      • Phosphomannose isomerase antibody
      • PMI antibody
      see all

    Anti-Mannose Phosphate Isomerase antibody images

    • All lanes : Anti-Mannose Phosphate Isomerase antibody (ab67357) at 1/500 dilution

      Lane 1 : Mannose Phosphate Isomerase transfected 293T cell lysate
      Lane 2 : Non transfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 46 kDa
      Observed band size : 46 kDa

    References for Anti-Mannose Phosphate Isomerase antibody (ab67357)

    ab67357 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"