Anti-MAP1 antibody (ab25954)

Overview

• Product nameAnti-MAP1 antibody
  See all MAP1 primary antibodies
• Description
  Rabbit polyclonal to MAP1
• Specificityab25954 recognises MAP-1.
• Tested applicationsSuitable for: WBmore details
• Species reactivity
  Reacts with: Mouse, Human
  
• Immunogen

  A 15 amino acid synthetic peptide from near the center of MAP-1(Human)

• Positive control
  • EL4 cell lysate.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Store at +4°C.
• Storage bufferPreservative: 0.02% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• ClonalityPolyclonal
• IsotypeIgG
• Research areas
  • Cell Biology
  • Apoptosis
  • Intracellular
  • Bcl2 Family

Associated products

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
• Positive Controls
  • EL4 whole cell lysate (ab7183)

Applications

Target

• FunctionRequired for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.
• Tissue specificityUbiquitously expressed with higher levels in heart and brain.
• Sequence similaritiesBelongs to the PNMA family.
• DomainThe BH3-like domain is required for association with BAX and for mediating apoptosis. The three BH domains (BH1, BH2, and BH3) of BAX are all required for mediating protein-protein interaction.

• Target information above from: UniProt accession Q96BY2 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 64112 Human
  • Entrez Gene: 64113 Mouse
  • Omim: 609485 Human
  • SwissProt: Q96BY2 Human
  • SwissProt: Q9ERH6 Mouse
  • Unigene: 24719 Human
  • Unigene: 291222 Mouse
• Alternative names
  • MAP 1 antibody
  • MAP-1 antibody
  • MAP1 antibody

  • MOAP1 antibody
  • MOAP1_HUMAN antibody
  • Modulator of apoptosis 1 antibody
  • Modulator of Apoptosis antibody
  • Paraneoplastic antigen like 4 antibody
  • Paraneoplastic antigen Ma4 antibody
  • paraneoplastic Ma antigen family member 4 antibody
  • PNMA4 antibody

  see all