Overview

  • Product nameAnti-MAP1S antibody
    See all MAP1S primary antibodies
  • Description
    Mouse monoclonal to MAP1S
  • Tested applicationsSuitable for: WB, ELISA, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 929-1027 of Human MAP1S with a proprietary tag (NP_060644).

  • Positive control
    • Recombinant Protein.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Constituent: 99% PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa

Applications

Our Abpromise guarantee covers the use of ab118111 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 112 kDa. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
ELISA Use at an assay dependent dilution.
Sandwich ELISA Use a concentration of 10 µg/ml.

Target

  • FunctionMicrotubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule-organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles.
  • Tissue specificityExpressed in neurons (at protein level). Expressed in spermatocytes, spermatids and spermatozoa. Expressed in the cerebral cortex. Highly expressed in testis. Moderately expressed in the brain, colon, heart, kidney, liver, lung, placenta, small intestine, spleen and stomach. Weakly expressed in muscle.
  • Sequence similaritiesBelongs to the MAP1 family.
  • DomainThe N-terminus of the heavy chain associates with the C-terminus of the light chain to form the heterodimer complex (By similarity). Its C-terminal part of the heavy chain interacts with ESR1.
  • Cellular localizationNucleus. Cytoplasm > cytosol. Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > spindle. Detected in filopodia-like protrusions and synapses (By similarity). Detected in perinuclear punctate network corresponding to mitochondrial aggregates and in the nucleus in cells exhibiting apoptosis. Associated specifically with microtubules stabilized by paclitaxel and colocalizes with RASSF1 isoform A. In interphase cells, shows a diffuse cytoplasmic staining with partial localization to the microtubules. During the different stages of mitosis detected at the spindle microtubules.
  • Information by UniProt
  • Database links
  • Alternative names
    • BPY2-interacting protein 1 antibody
    • BPY2IP1 antibody
    • C19orf5 antibody
    • FLJ10669 antibody
    • MAP-1S antibody
    • MAP1S antibody
    • MAP1S light chain antibody
    • MAP1S_HUMAN antibody
    • MAP8 antibody
    • MGC133087 antibody
    • microtubule-associated protein 1S antibody
    • Microtubule-associated protein 8 antibody
    • Variable charge Y chromosome 2-interacting protein 1 antibody
    • VCY2-interacting protein 1 antibody
    • VCY2IP-1 antibody
    • VCY2IP1 antibody
    see all

Anti-MAP1S antibody images

  • Anti-MAP1S antibody (ab118111) at 5 µg/ml + recombinant immunogen at 0.2 µg
    Developed using the ECL technique

    Predicted band size : 112 kDa
  • ab118111 at 10 µg/ml as a capture antibody. The detection limit for recombinant tagged MAP1S is 0.1 ng/ml.

References for Anti-MAP1S antibody (ab118111)

ab118111 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab118111.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"