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Anti-MAP2 antibody [AA6] (ab24645)

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Overview

Product name

Anti-MAP2 antibody [AA6]
See all MAP2 products (18) ...

Description

Mouse monoclonal [AA6] to MAP2

Tested applications

WBmore details

Cross reactivity

Reacts with

Rat

Predicted to work with

all Mammals

Immunogen

Rat brain taxol stabilized microtubules.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.03% Thimerosal (merthiolate)
Constituents: PBS

Concentration

Concentration information loading...

Purity

Protein A purified

Primary antibody notes

This antibody will stain neuronal cell bodies and dendritic processes, and will not stain glial cells or axons. It is the best marker to distinguish dendrites from axons in the brain.

Clonality

Monoclonal

Clone number

AA6

Isotype

IgG2a

Applications

Show applications key

Our Abpromise guarantee covers the use of ab24645 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • WB

     

Application notes

WB: 1/1000. Predicted molecular weight: 280 kDa (MAP2 is made up of two ~280kDa apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at ~70kDa on SDS-PAGE gels).

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

Sequence similarities

Contains 3 Tau/MAP repeats.

Post-translational
modifications

MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.

Cellular localization

Cytoplasm > cytoskeleton.

Target information above from: UniProt accessionP11137 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • DKFZp686I2148 antibody
  • Dendrite specific MAP antibody
  • Dendrite specific MAP antibody
  • DKFZp686I2148 antibody
  • MAP 2 antibody
  • MAP-2 antibody
  • MAP2 antibody
  • MAP2_HUMAN antibody
  • MAP2A antibody
  • MAP2B antibody
  • MAP2C antibody
  • Microtubule associated protein 2 antibody
  • Microtubule-associated protein 2 antibody
  • Mtap 2 antibody
  • Mtap 2 antibody
see all

References for Anti-MAP2 antibody [AA6] (ab24645)

ab24645 has not yet been referenced specifically in any publications.

Publishing research using ab24645? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"