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Products:Neuroscience >> Cell Type Marker >> Neuron marker >> Soma marker
Overview
Product name
Anti-MAP2 antibody [AA6]
See all MAP2 products (18) ...
Description
Mouse monoclonal [AA6] to MAP2
Tested applications
Cross reactivity
Reacts with
Rat
Predicted to work with
all Mammals
Immunogen
Rat brain taxol stabilized microtubules.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.03% Thimerosal (merthiolate)
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein A purified
Primary antibody notes
This antibody will stain neuronal cell bodies and dendritic processes, and will not stain glial cells or axons. It is the best marker to distinguish dendrites from axons in the brain.
Clonality
Monoclonal
Clone number
AA6
Isotype
IgG2a
Research areas
Stem Cells >> Neural Stem Cells >> Neuron Restricted Lineage
Neuroscience >> Cell Type Marker >> Neuron marker >> Dendrite marker
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microtubules >> MT Associated Proteins >> MAP
Neuroscience >> Cell Type Marker >> Neuron marker >> Soma marker
Applications
Show applications key
Our Abpromise guarantee covers the use of ab24645 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
Application notes
WB: 1/1000. Predicted molecular weight: 280 kDa (MAP2 is made up of two ~280kDa apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at ~70kDa on SDS-PAGE gels).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
Sequence similarities
Contains 3 Tau/MAP repeats.
Post-translational
modifications
MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localization
Cytoplasm > cytoskeleton.
Target information above from: UniProt accessionP11137
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- DKFZp686I2148 antibody
- Dendrite specific MAP antibody
- Dendrite specific MAP antibody
see all
Database links
References for Anti-MAP2 antibody [AA6] (ab24645)
ab24645 has not yet been referenced specifically in any publications.
Publishing research using ab24645? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"