Overview

  • Product nameAnti-MAP3K4 antibody
    See all MAP3K4 primary antibodies
  • Description
    Rabbit polyclonal to MAP3K4
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids 1065-1097 (surrounding C10810) of Human MAP3K4 (Accessions: Q9Y6R4, NP_006715.2, NP_005913.2)

  • Positive control
    • Human normal uterus cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab123714 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 182 kDa.

Target

  • FunctionComponent of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6.
  • Tissue specificityExpressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues.
  • Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • Cellular localizationCytoplasm > perinuclear region. Localized in perinuclear vesicular-like structures, probably Golgi-associated vesicles.
  • Information by UniProt
  • Database links
  • Alternative names
    • dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4) antibody
    • FLJ42439 antibody
    • KIAA0213 antibody
    • M3K4_HUMAN antibody
    • MAP three kinase 1 antibody
    • MAP/ERK kinase kinase 4 antibody
    • MAP3K4 antibody
    • MAPK/ERK kinase kinase 4 antibody
    • MAPKKK4 antibody
    • MEK kinase 4 antibody
    • MEKK 4 antibody
    • MEKK4 antibody
    • Mitogen-activated protein kinase kinase kinase 4 antibody
    • MTK1 antibody
    • predicted protein of HQ0412 antibody
    • PRO0412 antibody
    • RP3-473J16.4 antibody
    • SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of antibody
    see all

Anti-MAP3K4 antibody images

  • Anti-MAP3K4 antibody (ab123714) at 1/100 dilution + human normal uterus cell line lysates at 35 µg

    Predicted band size : 182 kDa

References for Anti-MAP3K4 antibody (ab123714)

ab123714 has not yet been referenced specifically in any publications.

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