Anti-MAP4K6 antibody - C-terminal (ab154256)

Overview

  • Product name
    Anti-MAP4K6 antibody - C-terminal
    See all MAP4K6 primary antibodies
  • Description
    Rabbit polyclonal to MAP4K6 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 901-1120 of Human MAP4K6 (Uniprot ID: Q8N4C8).

  • Positive control
    • HepG2 whole cell lysate; U87 xenograft; HeLa cells

Properties

Applications

Our Abpromise guarantee covers the use of ab154256 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 150 kDa.
IHC-P 1/100 - 1/1000.
ICC/IF 1/100 - 1/1000.

Target

  • Relevance
    MAP4K6 is a serine/threonine kinase belonging to the germinal center kinase (GCK) family. These kinases regulate a wide variety of cellular processes by coupling cell surface receptors to MAPK pathways. This kinase appears to act upstream of the JUN N-terminal pathway and may be involved in brain development. It may also play a role in the response to environmental stress, in cytoskeleton reorganization, cell adhesion, and cell motility. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
  • Cellular localization
    Cytoplasm. Cell junction; synapse; postsynaptic cell membrane; postsynaptic density. Cell projection; axon. Cell projection; dendrite. Isoform 4: Golgi apparatus
  • Database links
  • Alternative names
    • B55 antibody
    • GCK family kinase MiNK antibody
    • hMINK antibody
    • Map4k6 antibody
    • MAPK/ERK kinase kinase kinase 6 antibody
    • MEK (MAP/ERK) kinase kinase 6 antibody
    • MEK kinase kinase 6 antibody
    • MEKKK6 antibody
    • MGC21111 antibody
    • MINK 1 antibody
    • MINK antibody
    • MINK1 antibody
    • Misshapen like kinase 1 antibody
    • Misshapen NIKs Related kinase antibody
    • Misshapen/NIK related kinase antibody
    • Mitogen activated protein kinase kinase kinase kinase 6 antibody
    • RP23-122P1.6 antibody
    • Ysk2 antibody
    • ZC3 antibody
    see all

Images

  • Anti-MAP4K6 antibody - C-terminal (ab154256) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size: 150 kDa



    7.5% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded U87 xenograft tissue labeling MAP4K6 with ab154256 at 1/500 dilution.
  • Immunofluorescent analysis of paraformaldehyde-fixed HeLa cells labeling MAP4K6 with ab154256 at 1/200 dilution. Lower panel merged with DNA probe.

References

ab154256 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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