Overview

  • Product name
  • Description
    Rabbit polyclonal to MAPK11
  • Specificity
    This antibody does not cross-react with the alpha, gamma or delta forms.
  • Tested applications
    Suitable for: WB, IP, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic MAPK11 C terminal peptide (Human) conjugated to KLH

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.01% Sodium Azide
    Constituents: 50% Glycerol, Tris buffered saline
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    The antibody is affinity purified with MAPK11 C terminal peptide on agarose.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab80116 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Detects a band of approximately 30, 42 kDa (predicted molecular weight: 42 kDa).
IP Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.

Target

  • Function
    Kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. Phosphorylates preferentially transcription factor ATF2.
  • Tissue specificity
    Highest levels in the brain and heart. Also expressed in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
    Contains 1 protein kinase domain.
  • Domain
    The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
  • Post-translational
    modifications
    Dually phosphorylated on Thr-180 and Tyr-182, which activates the enzyme.
  • Information by UniProt
  • Database links
  • Alternative names
    • Human p38Beta MAP kinase mRNA complete cds antibody
    • MAP kinase 11 antibody
    • MAP kinase p38 beta antibody
    • MAPK 11 antibody
    • Mapk11 antibody
    • Mitogen activated protein kinase 11 antibody
    • Mitogen activated protein kinase p38 2 antibody
    • Mitogen activated protein kinase p38 beta antibody
    • Mitogen-activated protein kinase 11 antibody
    • Mitogen-activated protein kinase p38 beta antibody
    • MK11_HUMAN antibody
    • p38 2 antibody
    • p38-2 antibody
    • p38B antibody
    • p38Beta antibody
    • P38BETA2 antibody
    • PRKM11 antibody
    • Protein kinase mitogen activated 11 antibody
    • SAPK2 antibody
    • SAPK2B antibody
    • Stress activated protein kinase 2 antibody
    • Stress activated protein kinase 2b antibody
    • Stress-activated protein kinase 2 antibody
    see all

References

ab80116 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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