Anti-MAPK11 antibody - Carboxyterminal end (ab37937)

Overview

  • Product nameAnti-MAPK11 antibody - Carboxyterminal end
    See all MAPK11 primary antibodies
  • Description
    Rabbit polyclonal to MAPK11 - Carboxyterminal end
  • Tested applicationsSuitable for: ELISA, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide, selected from C terminal amino acids 356-372 of human MAPK11.

  • Positive control
    • Human placenta lysate, and human breast carcinoma and human hepatocarcinoma tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesEluted out with both high and low pH buffers and neutralized immediately after elution, followed by dialysis against PBS.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab37937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 42 kDa.
IHC-P 1/50 - 1/100.

Target

  • FunctionKinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. Phosphorylates preferentially transcription factor ATF2.
  • Tissue specificityHighest levels in the brain and heart. Also expressed in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
    Contains 1 protein kinase domain.
  • DomainThe TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
  • Post-translational
    modifications
    Dually phosphorylated on Thr-180 and Tyr-182, which activates the enzyme.
  • Information by UniProt
  • Database links
  • Alternative names
    • Human p38Beta MAP kinase mRNA complete cds antibody
    • MAP kinase 11 antibody
    • MAP kinase p38 beta antibody
    • MAPK 11 antibody
    • Mapk11 antibody
    • Mitogen activated protein kinase 11 antibody
    • Mitogen activated protein kinase p38 2 antibody
    • Mitogen activated protein kinase p38 beta antibody
    • Mitogen-activated protein kinase 11 antibody
    • Mitogen-activated protein kinase p38 beta antibody
    • MK11_HUMAN antibody
    • p38 2 antibody
    • p38-2 antibody
    • p38B antibody
    • p38Beta antibody
    • P38BETA2 antibody
    • PRKM11 antibody
    • Protein kinase mitogen activated 11 antibody
    • SAPK2 antibody
    • SAPK2B antibody
    • Stress activated protein kinase 2 antibody
    • Stress activated protein kinase 2b antibody
    • Stress-activated protein kinase 2 antibody
    see all

Anti-MAPK11 antibody - Carboxyterminal end images

  • Anti-MAPK11 antibody - Carboxyterminal end (ab37937) at 1/100 dilution + Human placenta lysate

    Observed band size : 42 kDa (why is the actual band size different from the predicted?)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labeling MAPK11 with ab37937 at a 1/50 dilution.

     

References for Anti-MAPK11 antibody - Carboxyterminal end (ab37937)

ab37937 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab37937.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"