Overview

  • Product name
  • Description
    Rabbit polyclonal to MAPRE1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide between N terminal amino acids 51-79 of Human MAPRE1 (NP_036457.1), conjugated to KLH.

  • Positive control
    • Mouse brain tissue lysates; Human bladder carcinoma

Properties

Applications

Our Abpromise guarantee covers the use of ab107562 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 30 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
  • Tissue specificity
    Ubiquitously expressed.
  • Sequence similarities
    Belongs to the MAPRE family.
    Contains 1 CH (calponin-homology) domain.
    Contains 1 EB1 C-terminal domain.
  • Domain
    Composed of two functionally independent domains. The N-terminal domain forms an hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1.
  • Cellular localization
    Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome. Associated with the microtubule network at the growing distal tip of microtubules. Also enriched at the centrosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5530600P05Rik antibody
    • Adenomatous polyposis coli binding protein EB 1 antibody
    • Adenomatous polyposis coli binding protein EB1 antibody
    • AI462499 antibody
    • AI504412 antibody
    • APC binding protein EB 1 antibody
    • APC binding protein EB1 antibody
    • APC-binding protein EB1 antibody
    • AW260097 antibody
    • BIM1p antibody
    • D2Ertd459e antibody
    • EB 1 antibody
    • EB1 antibody
    • End binding protein 1 antibody
    • End-binding protein 1 antibody
    • fa01e12 antibody
    • fc23e11 antibody
    • fi33c06 antibody
    • MAPRE 1 antibody
    • MAPRE1 antibody
    • Mapre3 antibody
    • MARE1_HUMAN antibody
    • MGC117374 antibody
    • MGC129946 antibody
    • MGC52508 antibody
    • Microtubule associated protein RP/EB family member 1 antibody
    • Microtubule-associated protein RP/EB family member 1 antibody
    • wu:fa01e12 antibody
    • wu:fc23e11 antibody
    • wu:fi33c06 antibody
    • zgc:55428 antibody
    • zgc:77807 antibody
    • zgc:85755 antibody
    see all

Images

  • Anti-MAPRE1 antibody (ab107562) at 1/100 dilution + Mouse brain tissue lysates at 15 µg

    Predicted band size: 30 kDa

  • Immunohistochemistry analysis in formalin fixed and paraffin embedded human bladder carcinoma using 1/50 ab107562 followed by peroxidase conjugation of the secondary antibody and DAB staining.

References

ab107562 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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