The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/10 - 1/50.
1/200 - 1/500. Detects a band of approximately 95 kDa (predicted molecular weight: 89 kDa).
FunctionMay play a role in cytoskeletal stability.
Tissue specificityHighly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.
Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily. Contains 1 KA1 (kinase-associated) domain. Contains 1 protein kinase domain. Contains 1 UBA domain.
Cellular localizationCytoplasm > cytoskeleton. Appears to localize to an intracellular network.
ab60202, at 1/50 dilution, staining MARK1 in formalin fixed, paraffin-embedded human brain tissue by immunohistochemistry. ab60202 was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
References for Anti-MARK1 antibody (ab60202)
has not yet been referenced specifically in any publications.
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