The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 85 kDa (predicted molecular weight: 89 kDa).
FunctionMay play a role in cytoskeletal stability.
Tissue specificityHighly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.
Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily. Contains 1 KA1 (kinase-associated) domain. Contains 1 protein kinase domain. Contains 1 UBA domain.
Cellular localizationCytoplasm > cytoskeleton. Appears to localize to an intracellular network.