Anti-MASP1 antibody [MM0197-4F19] (ab89316)

Overview

  • Product name
    Anti-MASP1 antibody [MM0197-4F19]
    See all MASP1 primary antibodies
  • Description
    Mouse monoclonal [MM0197-4F19] to MASP1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment (Human)

Properties

  • Form
    Lyophilised:Reconstitute with 200µl PBS
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    MM0197-4F19
  • Isotype
    IgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab89316 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 79 kDa.

Target

  • Relevance
    MASP is a component of the bactericidal ra-reactive factor rarf which specifically binds to RA and R2 polysaccharides expressed by certain enterobacteria. It triggers the activation of complement cascade by activating the C4 and C2 components. It activates the C4 component by cleaving the alpha-chain of C4. The alternative-splicing product from MASP1 gene is called MASP3. MASP1 is associated with smaller MBL oligomers whereas MASP3 is found on larger oligomers. The substrate of MASP3 is unknown.
  • Cellular localization
    Secreted
  • Database links
  • Alternative names
    • Complement factor MASP-3 antibody
    • Complement factor MASP3 antibody
    • Complement-activating component of Ra-reactive factor antibody
    • CRARF antibody
    • Mannose binding lectin associated serine protease 1 antibody
    • Mannose binding protein associated serine protease antibody
    • Mannose-binding lectin-associated serine protease 1 antibody
    • Mannose-binding lectin-associated serine protease-1 antibody
    • MASP antibody
    • PRSS 5 antibody
    • Ra-reactive factor serine protease p100 antibody
    • RaRF antibody
    • Serine protease 5 antibody
    see all

References for Anti-MASP1 antibody [MM0197-4F19] (ab89316)

ab89316 has not yet been referenced specifically in any publications.

Product Wall

The epitope the antibody recognizes has not been mapped, as far as we know, but we know the immunogen that the antibody was generated against is a recombinant fragment of the human protein (Accession # NP_624302), from amino acid 450 to aa 728. http://...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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