Overview

  • Product name
  • Description
    Rabbit polyclonal to MASPIN
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Recombinant full length protein corresponding to Human MASPIN aa 1-231. Isoform 2 (BC020713).
    Sequence:

    MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDT ANEIGQVLHFENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNL STEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILAD NSVNDQTKILVVNAAYFVGKWMKKFPESETKECPFRVNKVCGAACSSKRS PIIDVKNDRDRVGHKSIPMRNLRARPAKCLS


    Database link: P36952-2

  • Positive control
    • Mouse esophagus tissue and Human cervical cancer tissue lysates; Human esophagus cancer tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab182785 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 25 kDa.
IHC-P 1/100 - 1/300.

Target

  • Function
    Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
  • Tissue specificity
    Normal mammary epithelial cells.
  • Sequence similarities
    Belongs to the serpin family. Ov-serpin subfamily.
  • Cellular localization
    Secreted > extracellular space.
  • Information by UniProt
  • Database links
  • Alternative names
    • Maspin antibody
    • Ovalbumin antibody
    • Peptidase inhibitor 5 antibody
    • PI-5 antibody
    • PI5 antibody
    • protease inhibitor 5 (maspin) antibody
    • Protease inhibitor 5 antibody
    • Serine (or cysteine) peptidase inhibitor, clade B, member 5 antibody
    • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5 antibody
    • Serpin B5 antibody
    • serpin family B member 5 antibody
    • Serpin peptidase inhibitor antibody
    • Serpin peptidase inhibitor, clade B (ovalbumin), member 5 antibody
    • Serpinb5 antibody
    • SPB5_HUMAN antibody
    • Spi5 antibody
    • Spi7 antibody
    see all

Images

  • All lanes : Anti-MASPIN antibody (ab182785) at 1/1000 dilution

    Lane 1 : Mouse esophagus tissue lysate
    Lane 2 : Human cervical cancer tissue lysate

    Lysates/proteins at 40 µg per lane.

    Secondary
    Goat anti Rabbit IgG at 1/10000 dilution

    Predicted band size : 25 kDa


    Exposure time : 13 seconds
  • Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ab182785 at dilution 1/60,on the right is trested with the fusion protein

References

ab182785 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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