Overview

  • Product name
  • Description
    Rabbit polyclonal to MATK - Aminoterminal end
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A KLH conjugated synthetic peptide selected from the sequence of Human MATK within amino acids 1-100.

  • Positive control
    • Mouse thymus tissue lysate, Human hepatocarcinoma tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    This antibody was purified through a protein G column and eluted out with both high and low pH buffers. It was neutralized immediately after elution, followed by dialysis against PBS.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab37824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).
ELISA 1/1000.
IHC-P 1/50 - 1/100.

Target

  • Function
    Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
  • Tissue specificity
    Expressed in various myeloid cell lines, detected in brain and lung.
  • Sequence similarities
    Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • CHK antibody
    • Csk homologous kinase antibody
    • Csk type protein tyrosine kinase antibody
    • CTK antibody
    • DKFZp434N1212 antibody
    • EC 2.7.10.2 antibody
    • Hematopoietic consensus tyrosine lacking kinase antibody
    • Hematopoietic consensus tyrosine-lacking kinase antibody
    • HHYLTK antibody
    • Hydroxyaryl protein kinase antibody
    • HYL antibody
    • HYL tyrosine kinase antibody
    • HYLTK antibody
    • Leukocyte carboxyl terminal src kinase related antibody
    • Lsk antibody
    • matK antibody
    • MATK_HUMAN antibody
    • Megakaryocyte associated tyrosine kinase antibody
    • Megakaryocyte associated tyrosine protein kinase antibody
    • Megakaryocyte-associated tyrosine-protein kinase antibody
    • MGC1708 antibody
    • MGC2101 antibody
    • Protein kinase HYL antibody
    • Tyrosine kinase MATK antibody
    • Tyrosine protein kinase CTK antibody
    • Tyrosine-protein kinase CTK antibody
    • Tyrosylprotein kinase antibody
    see all

Images

  • Anti-MATK antibody (ab37824) at 1/100 dilution + Mouse thymus tissue lysate

    Predicted band size : 56 kDa
    Observed band size : 56 kDa
  • ab37824, at a 1/50 dilution, staining MATK in Human hepatocarcinoma by Immunohistochemistry, Formalin fixed and Paraffin embedded tissue. ab37284 was peroxidase-conjugated to the secondary antibody, followed by AEC staining.

    This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

References

ab37824 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab37824.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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