Overview

  • Product nameAnti-Matrin 3 antibody [2539C3a]
    See all Matrin 3 primary antibodies
  • Description
    Mouse monoclonal [2539C3a] to Matrin 3
  • Tested applicationsSuitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human MATR3 protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab53748 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 95 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • FunctionMay play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.
  • Involvement in diseaseDefects in MATR3 are the cause of myopathy distal type 2 (MPD2) [MIM:606070]; also called vocal cord and pharyngeal dysfunction with distal myopathy (VCPDM). MPD2 is a muscular disorder characterized by distal weakness, with onset in hands and feet, associated with vocal cord and pharyngeal weakness causing a nasal voice and swallowing disorders.
  • Sequence similaritiesContains 1 matrin-type zinc finger.
    Contains 2 RRM (RNA recognition motif) domains.
  • Cellular localizationNucleus matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • ALS21 antibody
    • KIAA0723 antibody
    • Matr3 antibody
    • MATR3_HUMAN antibody
    • Matrin-3 antibody
    • Matrin3 antibody
    • MPD2 antibody
    • VCPDM antibody
    • Vocal cord and pharyngeal weakness with distal myopathy antibody
    see all

Anti-Matrin 3 antibody [2539C3a] images

  • Anti-Matrin 3 antibody [2539C3a] (ab53748) + recombinant immunising protein

    Predicted band size : 95 kDa

References for Anti-Matrin 3 antibody [2539C3a] (ab53748)

This product has been referenced in:
  • Antrobus R  et al. Proteomic analysis of cells in the early stages of herpes simplex virus type-1 infection reveals widespread changes in the host cell proteome. Proteomics 9:3913-27 (2009). Read more (PubMed: 19670248) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"