Recombinant
RabMAb

Anti-Matrin 3 antibody [EPR10634(B)] (ab151739)

Overview

  • Product name
    Anti-Matrin 3 antibody [EPR10634(B)]
    See all Matrin 3 primary antibodies
  • Description
    Rabbit monoclonal [EPR10634(B)] to Matrin 3
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
    Unsuitable for: Flow Cyt or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in the Human Matrin 3 protein (P43243).

  • Positive control
    • WB: Fetal kidney, HeLa, MCF-7, and HepG2 cell lysates. IHC: Human colon and endometrial carcinoma tissue. IF: MCF-7 cells.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab151739 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/50000. Predicted molecular weight: 95 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt or IP.
  • Target

    • Function
      May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.
    • Involvement in disease
      Defects in MATR3 are the cause of myopathy distal type 2 (MPD2) [MIM:606070]; also called vocal cord and pharyngeal dysfunction with distal myopathy (VCPDM). MPD2 is a muscular disorder characterized by distal weakness, with onset in hands and feet, associated with vocal cord and pharyngeal weakness causing a nasal voice and swallowing disorders.
    • Sequence similarities
      Contains 1 matrin-type zinc finger.
      Contains 2 RRM (RNA recognition motif) domains.
    • Cellular localization
      Nucleus matrix.
    • Information by UniProt
    • Database links
    • Alternative names
      • ALS21 antibody
      • KIAA0723 antibody
      • Matr3 antibody
      • MATR3_HUMAN antibody
      • Matrin-3 antibody
      • Matrin3 antibody
      • MPD2 antibody
      • VCPDM antibody
      • Vocal cord and pharyngeal weakness with distal myopathy antibody
      see all

    Images

    • All lanes : Anti-Matrin 3 antibody [EPR10634(B)] (ab151739) at 1/10000 dilution

      Lane 1 : Human fetal kidney lysates
      Lane 2 : HeLa cell lysates
      Lane 3 : MCF-7 cell lysates
      Lane 4 : HepG2 cell lysates

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Standard HRP labeled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 95 kDa

    • Immunohistochemical analysis of paraffin-embedded human colon tissue labeling Matrin 3 with ab151739 at 1/50.
    • Immunohistochemical analysis of paraffin-embedded endometrial carcinoma labeling Matrin 3 with ab151739 at 1/50.
    • Immunofluorescence analysis of MCF-7 cells labeling Matrin 3 with ab151739 at 1/100.

    References

    ab151739 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab151739.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up