HRP Anti-Matrix protein 1 antibody (ab21008)
Key features and details
- HRP Goat polyclonal to Matrix protein 1
- Suitable for: ELISA, ICC/IF, WB
- Reacts with: Influenza A
- Conjugation: HRP
- Isotype: IgG
Overview
-
Product name
HRP Anti-Matrix protein 1 antibody
See all Matrix protein 1 primary antibodies -
Description
HRP Goat polyclonal to Matrix protein 1 -
Host species
Goat -
Conjugation
HRP -
Tested applications
Suitable for: ELISA, ICC/IF, WBmore details
Unsuitable for: IHC -
Species reactivity
Reacts with: Influenza A -
Immunogen
Full length native protein (purified) corresponding to Matrix protein 1. Purified M1 protein, Influenza A-Phillipines (H3N2).
-
General notes
Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
The antibody is covalently coupled to a highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is removed.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
Preservative: 0.002% Thimerosal (merthiolate)
Constituents: PBS, 1% BSA -
Concentration information loading...
-
Purity
IgG fraction -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Recombinant Protein
-
Related Products
- TMB ELISA Substrate (Highest Sensitivity) (ab171522)
- TMB ELISA Substrate (High Sensitivity) (ab171523)
- TMB ELISA Substrate (Fast Kinetic Rate) (ab171524)
- TMB ELISA Substrate (Slow Kinetic Rate) (ab171525)
- TMB ELISA Substrate (Slower Kinetic Rate) (ab171526)
- TMB ELISA Substrate (Slowest Kinetic Rate) (ab171527)
- 450 nm Stop Solution for TMB Substrate (ab171529)
- 650 nm Stop Solution for TMB Substrate (ab171531)
- Immunoassay Blocking Buffer (ab171534)
- Immunoassay Blocking (BSA Free) (ab171535)
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab21008 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ELISA |
Use at an assay dependent dilution.
|
|
ICC/IF |
Use at an assay dependent dilution.
|
|
WB |
Use a concentration of 1 µg/ml.
|
Notes |
---|
ELISA
Use at an assay dependent dilution. |
ICC/IF
Use at an assay dependent dilution. |
WB
Use a concentration of 1 µg/ml. |
Target
-
Relevance
Influenza virus type A matrix protein, also known as M1, is composed of a 252 amino acid sequence and is type-specific in influenza viruses. It is located inside the viral lipid envelope and plays a key role in virus assembly and replication. M1 can be isolated from particles by removing the envelope with detergents and reducing the pH to 4.0. Influenza viruses are a common and widely spread infectious agent. Like many other viruses, influenza virus are constantly undergoing mutations and thereby avoiding the immune system. The Influenza A Virus M proteins form a continuous shell on the inner side of the lipid bilayer, maintaining the structural integrity of the virus particle through hydrophobic interactions. -
Cellular localization
Cytoplasmic -
Database links
- Entrez Gene: 1461001 Influenza A
- Entrez Gene: 956527 Influenza A
- SwissProt: P03485 Influenza A
-
Alternative names
- M1 antibody
- Matrix Protein 1 antibody
- Matrix Protein I antibody
- Membrane matrix protein M1 antibody
Protocols
Datasheets and documents
-
SDS download
-
Datasheet download
References (1)
ab21008 has been referenced in 1 publication.
- Poon LL et al. Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice. J Immunol 182:3063-71 (2009). WB . PubMed: 19234203