Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab5023 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Additional notes

    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human Maxi K+ beta, catalog ab5023. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • BK channel beta subunit
    • BK channel subunit beta 1
    • BKbeta
    • BKbeta1
    • Calcium activated potassium channel subfamily M subunit beta 1
    • Calcium activated potassium channel subunit beta
    • Calcium activated potassium channel subunit beta 1
    • Charybdotoxin receptor subunit beta 1
    • Hbeta1
    • hslo beta
    • K(VCA)beta
    • K(VCA)beta 1
    • KCNMB 1
    • KCNMB1
    • Large conductance Ca2+ activated K+ channel beta 1 subunit
    • Maxi K channel beta subunit
    • Maxi K channel subunit beta 1
    • Potassium large conductance calcium activated channel subfamily M beta member 1
    • SLO beta
    • Slo beta 1
    see all
  • Relevance
    MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits.
  • Cellular localization
    Membrane; multi-pass membrane protein

References

This product has been referenced in:
  • Navarro-Antolín J  et al. Decreased expression of maxi-K+ channel beta1-subunit and altered vasoregulation in hypoxia. Circulation 112:1309-15 (2005). Read more (PubMed: 16116057) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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