Anti-MBD2 Interacting Zinc Finger MIZF antibody (ab87095)

Overview

  • Product nameAnti-MBD2 Interacting Zinc Finger MIZF antibody
  • Description
    Rabbit polyclonal to MBD2 Interacting Zinc Finger MIZF
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide from within residues: FKDRSKLREH LRSHTQEKVV ACPTCGGMFA NNTKFLDHIR RQTSLDQQHF, corresponding to internal sequence amino acids 180-229 of Human MBD2 Interacting Zinc Finger MIZF (NP_945322)

  • Positive control
    • Transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab87095 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 60 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionTranscriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter.
  • Tissue specificityUbiquitous. Highly expressed in brain, heart, skeletal muscle, spleen, kidney, small intestine, placenta and liver.
  • Sequence similaritiesContains 9 C2H2-type zinc fingers.
  • Post-translational
    modifications
    Ubiquitinated. Ubiquitination may lead to proteasome-mediated degradation.
  • Cellular localizationNucleus. Associated with discrete nuclear foci.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp434F162 antibody
    • HiNF-P antibody
    • HINFP antibody
    • HINFP_HUMAN antibody
    • Histone H4 gene specific protein HiNF P antibody
    • Histone H4 transcription factor antibody
    • Histone nuclear factor P antibody
    • MBD2 (methyl-CpG-binding protein)-interacting zinc finger protein antibody
    • MBD2 interacting zinc finger 1 antibody
    • MBD2 interacting zinc finger protein antibody
    • MBD2-interacting zinc finger protein antibody
    • Methyl CpG binding protein 2 interacting zinc finger protein antibody
    • Methyl-CpG-binding protein 2-interacting zinc finger protein antibody
    • MIZF antibody
    • ZNF743 antibody
    see all

Anti-MBD2 Interacting Zinc Finger MIZF antibody images

  • Anti-MBD2 Interacting Zinc Finger MIZF antibody (ab87095) at 1 µg/ml + Transfected 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 60 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 65 kDa. We are unsure as to the identity of these extra bands.

References for Anti-MBD2 Interacting Zinc Finger MIZF antibody (ab87095)

ab87095 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"