General notesab94293 is a 293T cell transfected lysate in which Human MBD3 has been transiently over-expressed using a pCMV-MBD3 plasmid. The lysate is provided in 1 x Sample Buffer. Note: For more details about how the transfected lysate was prepared view preparation notes
BackgroundFunction: Does not bind DNA by itself. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing.
Similarity: Contains 1 MBD (methyl-CpG-binding) domain.