Overview

  • Product name
    Anti-MC1 Receptor antibody
    See all MC1 Receptor primary antibodies
  • Description
    Rabbit polyclonal to MC1 Receptor
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human MC1 Receptor. The exact sequence is proprietary.
    Database link: Q01726

  • Positive control
    • Mouse intestinum tenue tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab180776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 35 kDa.

Target

  • Function
    Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
  • Tissue specificity
    Melanocytes and corticoadrenal tissue.
  • Involvement in disease
    Genetic variations in MC1R are a cause of susceptibility to cutaneous malignant melanoma type 5 (CMM5) [MIM:613099]. Malignant melanoma is a malignant neoplasm of melanocytes, arising de novo or from a pre-existing benign nevus, which occurs most often in the skin but also may involve other sites.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CMM5 antibody
    • MC1-R antibody
    • MC1R antibody
    • Melanocortin 1 receptor antibody
    • Melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) antibody
    • Melanocortin receptor 1 antibody
    • Melanocyte-stimulating hormone receptor antibody
    • Melanotropin receptor antibody
    • MSH-R antibody
    • MSHR antibody
    • MSHR_HUMAN antibody
    • SHEP2 antibody
    see all

Images

  • Anti-MC1 Receptor antibody (ab180776) at 1/500 dilution + Mouse intestinum tenue tissue lysate

    Predicted band size : 35 kDa

References

ab180776 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab180776.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up