Overview

  • Product name
    Anti-MC2 receptor antibody
    See all MC2 receptor primary antibodies
  • Description
    Rabbit polyclonal to MC2 receptor
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant full length protein corresponding to Human MC2 receptor aa 1-297.
    Sequence:

    MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVF KNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFET TADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVV LTVIWTFCTGTGITMVIFSHHVPTVITFTSLFPLMLVFILCLYVHMFLLA RSHTRKISTLPRANMKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPY CACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRDAFKKMIFCSRYW


    Database link: Q01718

  • Positive control
    • 293 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab180793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Predicted molecular weight: 34 kDa.

Target

  • Function
    Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase.
  • Tissue specificity
    Melanocytes and corticoadrenal tissue.
  • Involvement in disease
    Defects in MC2R are the cause of glucocorticoid deficiency type 1 (GCCD1) [MIM:202200]; also known as familial glucocorticoid deficiency type 1 (FGD1). GCCD1 is an autosomal recessive disorder due to congenital insensitivity or resistance to adrenocorticotropin (ACTH). It is characterized by progressive primary adrenal insufficiency, without mineralocorticoid deficiency.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACTH receptor antibody
    • ACTH-R antibody
    • ACTHR antibody
    • ACTHR_HUMAN antibody
    • Adrenocorticotropic hormone receptor antibody
    • Adrenocorticotropin receptor antibody
    • Corticotropin receptor antibody
    • MC2 receptor antibody
    • MC2-R antibody
    • MC2R antibody
    • Melanocortin 2 receptor (adrenocorticotropic hormone) antibody
    • Melanocortin 2 receptor antibody
    • Melanocortin receptor 2 antibody
    see all

Images

  • Anti-MC2 receptor antibody (ab180793) at 1/1000 dilution + 293 cell lysate

    Predicted band size : 34 kDa

References

ab180793 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab180793.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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