Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab92287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 37 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.
    • Tissue specificity
      Expressed in the brain but not in the melanoma cells.
    • Sequence similarities
      Belongs to the G-protein coupled receptor 1 family.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • MC-2 antibody
      • MC2 antibody
      • MC5 R antibody
      • MC5-R antibody
      • MC5R antibody
      • MC5R_HUMAN antibody
      • Melanocortin 5 receptor antibody
      • Melanocortin receptor 5 antibody
      see all

    Images

    • Anti-MC5 Receptor antibody (ab92287) at 0.3 µg/ml + Mouse Muscle lysate at 35 µg

      Predicted band size : 37 kDa
      Observed band size : 37 kDa
      Additional bands at : 30 kDa. We are unsure as to the identity of these extra bands.

    References

    This product has been referenced in:
    • Simamura E  et al. Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5. PLoS One 10:e0123232 (2015). Read more (PubMed: 25860801) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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