Overview

  • Product name
    Anti-MCF2 antibody
  • Description
    Rabbit polyclonal to MCF2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide between 803-833 amino acids from the C-terminal region of Human MCF2 (NP_001165347.1 , NP_001165348.1 , NP_001165350.1 , NP_005360.3 ,NP_001093325.1 , NP_001165349.1).

  • Positive control
    • K562 cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab112588 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 108 kDa.

Target

  • Relevance
    Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.
  • Cellular localization
    Cytoplasm Isoform 1: Membrane Isoform 3: Membrane. Note: Colocalizes with CDC42 to plasma membrane.
  • Database links
  • Alternative names
    • DBL antibody
    • DBL-transforming protein antibody
    • MCF2 antibody
    • MCF2-transforming protein antibody
    • Proto-oncogene DBL antibody
    • Proto-oncogene MCF-2 antibody
    see all

Images

  • Anti-MCF2 antibody (ab112588) at 1/100 dilution + K562 cell line lysate at 35 µg

    Predicted band size : 108 kDa

References

ab112588 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab112588.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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