Overview

  • Product nameAnti-MCHR antibody
    See all MCHR primary antibodies
  • Description
    Rabbit polyclonal to MCHR
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide conjugated to KLH, from the C terminal region of Human MCHR.

  • Positive control
    • Human brain (substantia nigra) tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab115474 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 - 18 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • RelevanceMCHR, a member of the G protein coupled receptor family 1, is an integral plasma membrane protein which binds melanin concentrating hormone. MCHR can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, MCHR does not seem to bind somatostatin.
  • Cellular localizationCell Membrane; multi-pass membrane protein
  • Database links
  • Alternative names
    • G protein coupled receptor 24 antibody
    • GPCR MCH1 antibody
    • GPCR SLC/MCH1 antibody
    • GPR24 antibody
    • MCH 1R antibody
    • MCH receptor 1 antibody
    • MCH-1R antibody
    • MCH-R1 antibody
    • MCH1R antibody
    • MCHR antibody
    • MCHR-1 antibody
    • Melanin concentrating hormone receptor 1 antibody
    • SLC-1 antibody
    • SLC1 antibody
    • Somatostatin receptor like protein antibody
    see all

Anti-MCHR antibody images

  • ab115474 at 10-18ug/ml staining MCHR in Formalin-fixed, Paraffin-embedded Human brain (substantia nigra) tissue by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen

References for Anti-MCHR antibody (ab115474)

ab115474 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"