Anti-MCL1 antibody [Y37] (ab32087)

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ab32087 has been referenced in 42 publications.

  • Li H  et al. Downregulation of MCL-1 and upregulation of PUMA using mTOR inhibitors enhance antitumor efficacy of BH3 mimetics in triple-negative breast cancer. Cell Death Dis 9:137 (2018). PubMed: 29374168
  • Ma L  et al. Long non-coding RNA XIST promotes cell growth and invasion through regulating miR-497/MACC1 axis in gastric cancer. Oncotarget 8:4125-4135 (2017). WB ; Human . PubMed: 27911852
  • Peperzak V  et al. Functional disparities among BCL-2 members in tonsillar and leukemic B-cell subsets assessed by BH3-mimetic profiling. Cell Death Differ 24:111-119 (2017). PubMed: 27689871
  • Fischer A  et al. Chlamydia trachomatis-containing vacuole serves as deubiquitination platform to stabilize Mcl-1 and to interfere with host defense. Elife 6:N/A (2017). PubMed: 28347402
  • Tian C  et al. ABCG1 as a potential oncogene in lung cancer. Exp Ther Med 13:3189-3194 (2017). PubMed: 28588672
  • Zhang X  et al. Upregulation of microRNA-125b by G-CSF promotes metastasis in colorectal cancer. Oncotarget 8:50642-50654 (2017). WB ; Human . PubMed: 28881590
  • Zhang ZF  et al. MicroRNA-182 downregulates Wnt/ß-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9. Oncotarget 8:101345-101361 (2017). PubMed: 29254169
  • Kozaki T  et al. Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response. Proc Natl Acad Sci U S A 114:2681-2686 (2017). PubMed: 28213497
  • Wu Q  et al. Endothelial growth medium suppresses apoptosis of mesenchymal stem cells in vitro via decrease of miR-29a. Mol Med Rep 16:2675-2681 (2017). PubMed: 28713918
  • Meryet-Figuière M  et al. Atelocollagen-mediated in vivo siRNA transfection in ovarian carcinoma is influenced by tumor site, siRNA target and administration route. Oncol Rep 38:1949-1958 (2017). PubMed: 28791387
  • Ishii N  et al. Reduced FBXW7 expression in pancreatic cancer correlates with poor prognosis and chemotherapeutic resistance via accumulation of MCL1. Oncotarget 8:112636-112646 (2017). PubMed: 29348852
  • Lin J  et al. Mcl-1 inhibitor suppresses tumor growth of esophageal squamous cell carcinoma in a mouse model. Oncotarget 8:114457-114462 (2017). PubMed: 29383093
  • Ohmer M  et al. Anti-apoptotic Bcl-XL but not Mcl-1 contributes to protection against virus-induced apoptosis. Cell Death Dis 7:e2340 (2016). WB . PubMed: 27537523
  • Wu J  et al. Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity. Cell Death Dis 7:e2339 (2016). WB . PubMed: 27537522
  • Jiang ZX  et al. Roscovitine ameliorates endotoxin-induced uveitis through neutrophil apoptosis. Mol Med Rep 14:1083-90 (2016). WB ; Mouse . PubMed: 27279017
  • Li Q  et al. The effects of buthionine sulfoximine on the proliferation and apoptosis of biliary tract cancer cells induced by cisplatin and gemcitabine. Oncol Lett 11:474-480 (2016). WB ; Human . PubMed: 26870236
  • Lopez J  et al. Mito-priming as a method to engineer Bcl-2 addiction. Nat Commun 7:10538 (2016). WB . PubMed: 26833356
  • Hellvard A  et al. Inhibition of CDK9 as a therapeutic strategy for inflammatory arthritis. Sci Rep 6:31441 (2016). WB, IHC-P ; Mouse, Human . PubMed: 27511630
  • Gao ZY  et al. Metformin induces apoptosis via a mitochondria-mediated pathway in human breast cancer cells in vitro. Exp Ther Med 11:1700-1706 (2016). Human . PubMed: 27168791
  • Wang W  et al. FXR agonists enhance the sensitivity of biliary tract cancer cells to cisplatin via SHP dependent inhibition of Bcl-xL expression. Oncotarget 7:34617-29 (2016). WB ; Human . PubMed: 27127878
  • Štarha P  et al. Platinum(II) Iodido Complexes of 7-Azaindoles with Significant Antiproliferative Effects: An Old Story Revisited with Unexpected Outcomes. PLoS One 11:e0165062 (2016). WB ; Mouse . PubMed: 27906967
  • Bailey ML  et al. Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint. Genetics 201:885-95 (2015). WB ; Human . PubMed: 26354767
  • Martínez A  et al. Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches. PLoS One 10:e0123352 (2015). WB ; Human . PubMed: 25923732
  • Yang L  et al. Wnt modulates MCL1 to control cell survival in triple negative breast cancer. BMC Cancer 14:124 (2014). IHC-P ; Human . PubMed: 24564888
  • Kanatsu-Shinohara M  et al. Skp1-Cullin-F-box (SCF)-type ubiquitin ligase FBXW7 negatively regulates spermatogonial stem cell self-renewal. Proc Natl Acad Sci U S A 111:8826-31 (2014). WB ; Mouse . PubMed: 24879440
  • Fresquet V  et al. Acquired mutations in BCL2 family proteins conferring resistance to the BH3 mimetic ABT-199 in lymphoma. Blood 123:4111-9 (2014). WB ; Human . PubMed: 24786774
  • Huang H  et al. Mcl-1 promotes lung cancer cell migration by directly interacting with VDAC to increase mitochondrial Ca2+ uptake and reactive oxygen species generation. Cell Death Dis 5:e1482 (2014). PubMed: 25341036
  • Peng YF  et al. Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells. Autophagy 9:2056-68 (2013). WB ; Human . PubMed: 24157892
  • Shim G  et al. Enhanced intrapulmonary delivery of anticancer siRNA for lung cancer therapy using cationic ethylphosphocholine-based nanolipoplexes. Mol Ther 21:816-24 (2013). WB . PubMed: 23380818
  • Yallapu MM  et al. Novel curcumin-loaded magnetic nanoparticles for pancreatic cancer treatment. Mol Cancer Ther 12:1471-80 (2013). PubMed: 23704793
  • Cippà PE  et al. Targeting apoptosis to induce stable mixed hematopoietic chimerism and long-term allograft survival without myelosuppressive conditioning in mice. Blood 122:1669-77 (2013). PubMed: 23869083
  • Ragot K  et al. Absence of correlation between oxysterol accumulation in lipid raft microdomains, calcium increase, and apoptosis induction on 158N murine oligodendrocytes. Biochem Pharmacol 86:67-79 (2013). WB ; Mouse . PubMed: 23473804
  • Dal Col J  et al. Retinoic acid/alpha-interferon combination inhibits growth and promotes apoptosis in mantle cell lymphoma through Akt-dependent modulation of critical targets. Cancer Res 72:1825-35 (2012). Human . PubMed: 22311672
  • Christensen DJ  et al. SET oncoprotein overexpression in B-cell chronic lymphocytic leukemia and non-Hodgkin lymphoma: a predictor of aggressive disease and a new treatment target. Blood 118:4150-8 (2011). PubMed: 21844565
  • Zuccotti M  et al. Gatekeeper of pluripotency: A common Oct4 transcriptional network operates in mouse eggs and embryonic stem cells. BMC Genomics 12:345 (2011). ICC/IF ; Mouse . PubMed: 21729306
  • Hsieh AC  et al. Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E. Cancer Cell 17:249-61 (2010). Flow Cyt ; Mouse . PubMed: 20227039
  • Buron N  et al. Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilization. PLoS One 5:e9924 (2010). WB ; Human . PubMed: 20360986
  • Campbell CJ  et al. The human stem cell hierarchy is defined by a functional dependence on Mcl-1 for self-renewal capacity. Blood 116:1433-42 (2010). Flow Cyt ; Human . PubMed: 20525924
  • Bieghs L  et al. The effects of forodesine in murine and human multiple myeloma cells. Adv Hematol 2010:131895 (2010). WB ; Mouse . PubMed: 20981156
  • Staversky RJ  et al. Epithelial Ablation of Bcl-XL Increases Sensitivity to Oxygen without Disrupting Lung Development. Am J Respir Cell Mol Biol : (2009). PubMed: 19880821
  • Mavrakis KJ  et al. Tumorigenic activity and therapeutic inhibition of Rheb GTPase. Genes Dev 22:2178-88 (2008). WB ; Mouse . PubMed: 18708578
  • Wendel HG  et al. Dissecting eIF4E action in tumorigenesis. Genes Dev 21:3232-7 (2007). WB ; Mouse . PubMed: 18055695


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