Overview

  • Product nameAnti-MCP1 antibody [2H5] (Phycoerythrin)
    See all MCP1 primary antibodies
  • Description
    Armenian Hamster monoclonal [2H5] to MCP1 (Phycoerythrin)
  • ConjugationPhycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant Mouse MCP1 expressed in CHO cells

  • Positive control
    • 24-hour LPS-stimulated normal Human peripheral blood cells; fixed permabilized LPS-stimulated thioglycolated Mouse PEC cells

Properties

Applications

Our Abpromise guarantee covers the use of ab95558 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.25µg for 105 cells. Use at less than or equal to 0.25 µg per test. A test is defined as the amount (µg)/test of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 105 to 108 cells/test.



ab101026-Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody.

Target

  • FunctionChemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
  • Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
  • Post-translational
    modifications
    Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C-C motif chemokine 2 antibody
    • CCL2 antibody
    • CCL2_HUMAN antibody
    • Chemokine (C C motif) ligand 2 antibody
    • GDCF 2 antibody
    • GDCF-2 antibody
    • GDCF2 antibody
    • HC11 antibody
    • HSMCR30 antibody
    • JE antibody
    • MCAF antibody
    • MCP 1 antibody
    • MCP-1 antibody
    • MCP1 antibody
    • MGC9434 antibody
    • Monocyte chemoattractant protein 1 antibody
    • Monocyte chemotactic and activating factor antibody
    • Monocyte chemotactic protein 1 antibody
    • Monocyte secretory protein JE antibody
    • SCYA2 antibody
    • Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je) antibody
    • Small inducible cytokine A2 antibody
    • Small inducible cytokine subfamily A (Cys Cys), member 2 antibody
    • Small-inducible cytokine A2 antibody
    • SMC CF antibody
    • SMC-CF antibody
    • SMCCF antibody
    see all

Anti-MCP1 antibody [2H5] (Phycoerythrin) images

  • Flow cytometry staining of 24-hour LPS-stimulated normal Human peripheral blood cells with 0.25 µg of Armenian Hamster IgG Isotype Control PE (open histogram) or 0.25 µg of ab95558 (filled histogram). Cells in the monocyte gate were used for analysis.

References for Anti-MCP1 antibody [2H5] (Phycoerythrin) (ab95558)

This product has been referenced in:
  • Taal MW  et al. Mechanisms underlying renoprotection during renin-angiotensin system blockade. Am J Physiol Renal Physiol 280:F343-55 (2001). Read more (PubMed: 11208610) »
  • Luo Y  et al. Macrophage inflammatory protein-2 and KC induce chemokine production by mouse astrocytes. J Immunol 165:4015-23 (2000). Read more (PubMed: 11034412) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"