The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 11 kDa.
Use a concentration of 0.5 µg/ml.
FunctionChemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
Post-translational modificationsProcessing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant.
Monocyte chemotactic and activating factor antibody
Monocyte chemotactic protein 1 antibody
Monocyte secretory protein JE antibody
Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je) antibody
Small inducible cytokine A2 antibody
Small inducible cytokine subfamily A (Cys Cys), member 2 antibody
Small-inducible cytokine A2 antibody
SMC CF antibody
References for Anti-MCP1 antibody (ab18072)
This product has been referenced in:
Campbell SJ et al. Central nervous system injury triggers hepatic CC and CXC chemokine expression that is associated with leukocyte mobilization and recruitment to both the central nervous system and the liver. Am J Pathol166:1487-97 (2005).
Read more (PubMed: 15855648) »