Overview

  • Product name
  • Description
    Rabbit polyclonal to MCP2
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Recombinant full length protein (Mouse)

Properties

Applications

Our Abpromise guarantee covers the use of ab39625 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notes
    ELISA (direct): Use at a concentration of at least 0.5 µg/ml to detect murine MCP2.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 11 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
    • Tissue specificity
      Highest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, spleen and prostate.
    • Sequence similarities
      Belongs to the intercrine beta (chemokine CC) family.
    • Post-translational
      modifications
      N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • Ccl8 antibody
      • CCL8_HUMAN antibody
      • HC14 antibody
      • MCP-2 antibody
      • MCP-2(6-76) antibody
      • Monocyte chemoattractant protein 2 antibody
      • Monocyte chemotactic protein 2 antibody
      • SCYA10 antibody
      • SCYA8 antibody
      • Small-inducible cytokine A8 antibody
      see all

    References

    ab39625 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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