Overview

  • Product name
    Anti-MCP4 antibody (Biotin)
    See all MCP4 primary antibodies
  • Description
    Rabbit polyclonal to MCP4 (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: WB, ELISA, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length Human MCP4 protein, highly pure (>98%).

Properties

  • Form
    Lyophilised:Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • Purity
    IgG fraction
  • Purification notes
    ab83122 was purified by affinity chromatography and then biotinylated. Filter sterilised.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab83122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 11 kDa.
ELISA Use a concentration of 0.25 - 1 µg/ml.
Sandwich ELISA Use a concentration of 0.25 - 1 µg/ml.

Target

  • Function
    Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
  • Tissue specificity
    Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells.
  • Sequence similarities
    Belongs to the intercrine beta (chemokine CC) family.
  • Post-translational
    modifications
    One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C-C motif chemokine 13 antibody
    • CCL13 antibody
    • CCL13_HUMAN antibody
    • Chemokine (C C motif) ligand 13 antibody
    • CK beta 10 antibody
    • CK-beta-10 antibody
    • CKb10 antibody
    • MCP-4 antibody
    • MGC17134 antibody
    • Monocyte chemoattractant protein 4 antibody
    • Monocyte chemotactic protein 4 antibody
    • NCC 1 antibody
    • NCC-1 antibody
    • NCC1 antibody
    • New CC chemokine 1 antibody
    • SCYA13 antibody
    • SCYL1 antibody
    • short chain antibody
    • Small inducible cytokine A13 precursor antibody
    • Small inducible cytokine subfamily A (Cys Cys) member 13 antibody
    • Small-inducible cytokine A13 antibody
    see all

References for Anti-MCP4 antibody (Biotin) (ab83122)

ab83122 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab83122.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up