Overview

  • Product nameAnti-MCRS1 antibody
    See all MCRS1 primary antibodies
  • Description
    Mouse polyclonal to MCRS1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length MCRS1 protein (Human)

  • Positive control
    • MCRS1 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab67393 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 52 kDa (predicted molecular weight: 52 kDa).

Target

  • FunctionModulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. May be an inhibitor of TERT telomerase activity.
    Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
  • Tissue specificityDetected in testis, and at lower levels in spleen, thymus, prostate, uterus, small intestine, colon and leukocytes.
  • Sequence similaritiesContains 1 FHA domain.
  • Developmental stageCell-cycle regulated: levels are highest early in S phase; not detectable in G2.
  • Cellular localizationNucleus. Nucleus > nucleolus. In microspherules in the nucleolus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 58 kDa microspherule protein antibody
    • Cell cycle regulated factor (78 kDa) antibody
    • Cell cycle regulated factor p78 antibody
    • Cell cycle-regulated factor p78 antibody
    • ICP22BP antibody
    • INO80 complex subunit J antibody
    • MCRS 1 antibody
    • MCRS 2 antibody
    • MCRS1 antibody
    • MCRS1_HUMAN antibody
    • MCRS2 antibody
    • Microspherule protein 1 antibody
    • MSP 58 antibody
    • MSP58 antibody
    • p78 antibody
    see all

Anti-MCRS1 antibody images

  • All lanes : Anti-MCRS1 antibody (ab67393) at 1/500 dilution

    Lane 1 : MCRS1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 52 kDa
    Observed band size : 52 kDa

References for Anti-MCRS1 antibody (ab67393)

ab67393 has not yet been referenced specifically in any publications.

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