The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesELISA: Use at a concentration of 0.5 - 1.0 µg/ml. The detection limit for recombinant human M-CSF Receptor is approximately 0.15 ng/well.
WB: Use at a concentration of 0.1 - 0.2 µg/ml. The detection limit for recombinant human M-CSF Receptor is approximately 5 ng/lane under non-reducing and 25 ng/lane under reducing conditions. Predicted molecular weight: 81 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionProtein tyrosine-kinase transmembrane receptor for CSF1 and IL34.
Tissue specificityExpressed in bone marrow and in differentiated blood mononuclear cells.
Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 protein kinase domain.