Anti-MCT2 antibody (ab81262)
Key features and details
- Rabbit polyclonal to MCT2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MCT2 antibody
See all MCT2 primary antibodies -
Description
Rabbit polyclonal to MCT2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide derived from human MCT2 protein
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Positive control
- WB:Testis, spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocytes.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.08% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab81262 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/400. Predicted molecular weight: 52 kDa.
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Notes |
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WB
1/400. Predicted molecular weight: 52 kDa. |
Target
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Function
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter. -
Tissue specificity
High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells. -
Sequence similarities
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 9194 Human
- Omim: 603654 Human
- SwissProt: O60669 Human
- Unigene: 439643 Human
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Alternative names
- MCT 2 antibody
- MCT antibody
- Monocarboxylate transporter 2 antibody
see all
Datasheets and documents
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Datasheet download
References (1)
ab81262 has been referenced in 1 publication.
- Silva ECA et al. The clinicopathological significance of monocarboxylate transporters in testicular germ cell tumors. Oncotarget 9:20386-20398 (2018). PubMed: 29755659