Anti-MD1 antibody - Carboxyterminal end (ab62507)

Overview

  • Product name
    Anti-MD1 antibody - Carboxyterminal end
    See all MD1 primary antibodies
  • Description
    Rabbit polyclonal to MD1 - Carboxyterminal end
  • Specificity
    This antibody reacts with MD1
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A 14 amino acid synthetic peptide from near the carboxy terminus of human MD1

  • Positive control
    • Daudi cell lysate and human spleen tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab62507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 23 kDa (predicted molecular weight: 18 kDa).
IHC-P Use a concentration of 2 µg/ml.

Target

  • Function
    May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.
  • Tissue specificity
    Highly expressed in B-cells, monocytes and tonsil.
  • Cellular localization
    Secreted > extracellular space. Associated with CD180 at the cell surface.
  • Information by UniProt
  • Database links
  • Alternative names
    • BPAD antibody
    • dJ80N2.1 antibody
    • Ly 86 antibody
    • Ly-86 antibody
    • Ly86 antibody
    • LY86_HUMAN antibody
    • Lymphocyte antigen 86 antibody
    • Lymphocyte antigen 86 precursor antibody
    • Major affective disorder 1 antibody
    • MD 1 antibody
    • MD1 protein antibody
    • MD1 RP105 associated antibody
    • MMD 1 antibody
    • Protein MD 1 antibody
    • Protein MD-1 antibody
    • RP1-80N2.1 antibody
    see all

Images

  • Lane 1 : Anti-MD1 antibody - Carboxyterminal end (ab62507) at 0.5 µg/ml
    Lane 2 : Anti-MD1 antibody - Carboxyterminal end (ab62507) at 1 µg/ml
    Lane 3 : Anti-MD1 antibody - Carboxyterminal end (ab62507) at 2 µg/ml

    Lane 1 : Daudi cell lysate
    Lane 2 : Daudi cell lysate
    Lane 3 : Daudi cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 18 kDa
    Observed band size : 23 kDa (why is the actual band size different from the predicted?)
  • Immunohistochemistry of MD1 in paraffin embedded human spleen tissue section with ab62507 antibody at 2 µg/ml.

References

ab62507 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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