Anti-MD2 antibody [18H10] (FITC) (ab106105)

Overview

  • Product nameAnti-MD2 antibody [18H10] (FITC)
    See all MD2 primary antibodies
  • Description
    Mouse monoclonal [18H10] to MD2 (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Specificityab106105 reacts with MD2. However, it does not react with sMD2.
  • Tested applicationsSuitable for: Functional Studies, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    TLR4/MD2 expressing CHO cells/ chimeric TLR4/MD2 fusion protein

  • General notes


    The monoclonal antibody 18H10 is able to inhibit bacterial binding to MD2.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: None
    Constituents: 1% BSA, PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Primary antibody notesThe monoclonal antibody 18H10 is able to inhibit bacterial binding to MD2.
  • ClonalityMonoclonal
  • Clone number18H10
  • IsotypeIgG2b
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106105 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies Use at an assay dependent concentration.
Flow Cyt 1/50. ab91368-Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

Target

  • FunctionCooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.
  • Post-translational
    modifications
    N-glycosylated; high-mannose.
  • Cellular localizationSecreted > extracellular space.
  • Information by UniProt
  • Database links
  • Alternative names
    • ESOP 1 antibody
    • ESOP-1 antibody
    • ESOP1 antibody
    • LY 96 antibody
    • Ly-96 antibody
    • LY96 antibody
    • LY96_HUMAN antibody
    • Lymphocyte antigen 96 antibody
    • md 2 antibody
    • MD 2 protein antibody
    • MD2 protein antibody
    • Myeloid differentiation protein 2 antibody
    • Protein MD 2 antibody
    • Protein MD-2 antibody
    • Protein MD2 antibody
    see all

References for Anti-MD2 antibody [18H10] (FITC) (ab106105)

ab106105 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry.

This antibody to MD-2, clone 18H10, has been extensively published. For flow cytometry data please refer to the 4 publications below.


1. Pugin, J et al; Soluble MD-2 activity in plasma from patient...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"