Overview

  • Product nameAnti-MD2 antibody [4H1]
    See all MD2 primary antibodies
  • Description
    Mouse monoclonal [4H1] to MD2
  • SpecificityReacts with both the monomeric and polymeric forms of soluble Human MD2 and the MD2/Toll-like receptor 4 complex. Able to inhibit LPS binding to MD2. It does not cross-react with Mouse MD2.
  • Tested applicationsSuitable for: WB, ELISA, Functional Studies, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Does not react with: Mouse
  • Immunogen

    Baculovirally expressed His tagged Human MD2.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 0.1% BSA, PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesab106132 was 0.2 µm filtered prior to formulation.
  • ClonalityMonoclonal
  • Clone number4H1
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106132 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50. Predicted molecular weight: 19 kDa.
ELISA 1/50.
Functional Studies Use at an assay dependent dilution.
ICC/IF 1/50.

Target

  • FunctionCooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.
  • Post-translational
    modifications
    N-glycosylated; high-mannose.
  • Cellular localizationSecreted > extracellular space.
  • Information by UniProt
  • Database links
  • Alternative names
    • ESOP 1 antibody
    • ESOP-1 antibody
    • ESOP1 antibody
    • LY 96 antibody
    • Ly-96 antibody
    • LY96 antibody
    • LY96_HUMAN antibody
    • Lymphocyte antigen 96 antibody
    • md 2 antibody
    • MD 2 protein antibody
    • MD2 protein antibody
    • Myeloid differentiation protein 2 antibody
    • Protein MD 2 antibody
    • Protein MD-2 antibody
    • Protein MD2 antibody
    see all

References for Anti-MD2 antibody [4H1] (ab106132)

ab106132 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"