Overview

  • Product nameAnti-MDFI antibody
    See all MDFI primary antibodies
  • Description
    Rabbit polyclonal to MDFI
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide derived from internal sequence of Human MDFI.

  • Positive control
    • Extracts from Jurkat cells

Properties

Applications

Our Abpromise guarantee covers the use of ab110058 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 25 kDa.

Target

  • FunctionInhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways.
  • Sequence similaritiesBelongs to the MDFI family.
  • Cellular localizationNucleus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • I MF antibody
    • I mfa antibody
    • Inhibitor of MyoD family a antibody
    • Mdfi antibody
    • MDFI_HUMAN antibody
    • MyoD family inhibitor antibody
    • Myogenic repressor I-mf antibody
    • OTTHUMP00000016375 antibody
    • OTTHUMP00000016376 antibody
    • OTTHUMP00000196103 antibody
    • OTTHUMP00000196414 antibody
    • OTTHUMP00000196415 antibody
    see all

Anti-MDFI antibody images

  • All lanes : Anti-MDFI antibody (ab110058) at 1/500 dilution

    Lane 1 : Extracts from Jurkat cells
    Lane 2 : Extracts from Jurkat cells with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 25 kDa

References for Anti-MDFI antibody (ab110058)

ab110058 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"