The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/5000.
1/1000 - 1/10000.
RelevanceInvolved in the encapsidating of the genome in a ratio of 1 N per 6 ribonucleotides, resulting in the protection from nucleases. The nucleocapsid (NC) has an helical structure with either 12.35 or 11.64 N per turn, approximately 20nm in diameter, with a hollow central cavity approximately 5nm in diameter. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. N is released in the blood following lysis of measles infected cells, it interacts then with human FCGR2B on immune cells, inducing apoptosis and blocking inflammatory immune response. Ntail binds to a protein on human thymic epithelial cells, termed Nucleoprotein Receptor (NR), inducing growth arrest
Cellular localizationVirion. Host cytoplasm.
Measles nucleocapsid protein antibody
Nucleocapsid protein antibody
Anti-Measles nucleoprotein antibody [3E1] images
Western blot - Measles nucleoprotein antibody [3E1] (ab9397)
Immunoblot of measles NP using monoclonal antibody 3E1.
Antibody 3E1 at a concentration of 0.5 µg/ml.
Lane 1 - prestained marker proteins
lane 2 - recombinant measles NP.
References for Anti-Measles nucleoprotein antibody [3E1] (ab9397)
This product has been referenced in:
Ito M et al. Measles virus nonstructural C protein modulates viral RNA polymerase activity by interacting with host protein SHCBP1. J Virol87:9633-42 (2013).
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