Overview

  • Product nameAnti-Meckelin antibody
    See all Meckelin primary antibodies
  • Description
    Rabbit polyclonal to Meckelin
  • Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from C terminal domain of human Meckelin.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: Whole serum
  • PurityWhole antiserum
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab76786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 20512146
WB 1/100 - 1/1000. Predicted molecular weight: 112 kDa.
IHC-P 1/50 - 1/200.

Target

  • RelevanceMeckelin localizes to the primary cilium and to the plasma membrane. It functions in centriole migration to the apical membrane and formation of the primary cilium. Defects in the gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6).
  • Cellular localizationCell membrane; Multi-pass membrane protein
  • Database links
  • Alternative names
    • JBTS6 antibody
    • Meckel syndrome type 3 protein antibody
    • MKS3 antibody
    • NPHP11 antibody
    • TMEM67 antibody
    • TNEM67 antibody
    • Transmembrane protein 67 antibody
    see all

Anti-Meckelin antibody images

References for Anti-Meckelin antibody (ab76786)

This product has been referenced in:
  • Valente EM  et al. Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes. Nat Genet : (2010). ICC/IF ; Human . Read more (PubMed: 20512146) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"