• Product nameAnti-MEK4 antibody [7A6]
    See all MEK4 primary antibodies
  • Description
    Mouse monoclonal [7A6] to MEK4
  • Tested applicationsSuitable for: IHC-Pmore details
    Unsuitable for: IHC-Fr or WB
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Prokaryotic recombinant fusion protein corresponding to a 116 amino acid portion of the C-terminus of the human MKK4 molecule.

  • Positive control
    • Testis.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 15mM Sodium Azide
    Constituents: Tissue culture supernatant
  • PurityTissue culture supernatant
  • ClonalityMonoclonal
  • Clone number7A6
  • MyelomaP3-NS1/1-Ag4-1
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Associated products


Our Abpromise guarantee covers the use of ab49466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
  • Application notesIs unsuitable for IHC-Fr or WB.
  • Target

    • FunctionDual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).
    • Tissue specificityAbundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
    • Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
      Contains 1 protein kinase domain.
    • Post-translational
      Activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases.
    • Information by UniProt
    • Database links
    • Alternative names
      • c Jun N terminal kinase kinase 1 antibody
      • C-JUN N-terminal kinase kinase 1 antibody
      • Dual specificity mitogen activated protein kinase kinase 4 antibody
      • Dual specificity mitogen-activated protein kinase kinase 4 antibody
      • JNK Activated Kinase 1 antibody
      • JNK activating kinase 1 antibody
      • JNK-activating kinase 1 antibody
      • JNKK antibody
      • JNKK1 antibody
      • MAP kinase kinase 4 antibody
      • Map2k4 antibody
      • MAPK ERK kinase 4 antibody
      • MAPK/ERK kinase 4 antibody
      • MAPKK 4 antibody
      • MAPKK4 antibody
      • MEK 4 antibody
      • MEK4 antibody
      • Mitogen activated protein kinase kinase 4 antibody
      • MKK 4 antibody
      • MKK4 antibody
      • MP2K4_HUMAN antibody
      • PRKMK4 antibody
      • SAPK ERK kinase 1 antibody
      • SAPK/ERK kinase 1 antibody
      • SAPKK 1 antibody
      • SAPKK1 antibody
      • SEK1 antibody
      • SERK1 antibody
      • SKK1 antibody
      • Stress activated protein kinase kinase 1 antibody
      see all

    Anti-MEK4 antibody [7A6] images

    • Ab49466, at a dilution of 1/20, staining MKK4 in paraffin sections of human testis by Immunohistochemistry.
      Note cytoplasmic and nuclear staining of spermatogonia in the seminiferous tubules.

    References for Anti-MEK4 antibody [7A6] (ab49466)

    ab49466 has not yet been referenced specifically in any publications.

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